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Evidence Search

Search reputable indexed orthopaedic literature from multiple scholarly sources, classify the evidence, and link papers directly to wiki topics and cases.

Sources: PubMed, Europe PMC, Crossref

Linking results to Wiki: Osteoporosis — Pathophysiology and Management
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Results are classified automatically from source metadata across PubMed, Europe PMC, and Crossref.
PubMed Crossref
PubMed Guideline / Consensus Evidence High

Update on the role of bone turnover markers in the diagnosis and management of osteoporosis: a consensus paper from The European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO), International

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA | 2025 | Bhattoa HP, Vasikaran S, Trifonidi I, Kapoula G

[Indexed for MEDLINE] Conflict of interest statement: Declarations. Conflict of interest: H.P.B.: No conflict of interest; S.V.: No conflict of interest; I.T.: No conflict of interest; G.K.: No conflict of interest; G.L.: Received speaker fee from SNIBE; N.R.J.: Received bone turnover marker assays free of charge for research from ROCHE, IDS and DiaSorin for research purposes;...

PubMed Guideline / Consensus Evidence High

Screening for Osteoporosis to Prevent Fractures: US Preventive Services Task Force Recommendation Statement.

JAMA | 2025 | US Preventive Services Task Force, Nicholson WK, Silverstein M, Wong JB

[Indexed for MEDLINE] 12. Curr Opin Endocrinol Diabetes Obes. 2007 Dec;14(6):446-50. doi: 10.1097/MED.0b013e3282f15407. Glucocorticoid-induced osteoporosis. Berris KK(1), Repp AL, Kleerekoper M. Author information: (1)Department of Internal Medicine, Wayne State University, Detroit, Michigan, USA. PURPOSE OF REVIEW: To present an overview of the peer-reviewed literature relatin...

PubMed Guideline / Consensus Evidence High

European Consensus Statement on the diagnosis and management of osteoporosis in chronic kidney disease stages G4-G5D.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association | 2021 | Evenepoel P, Cunningham J, Ferrari S, Haarhaus M

[Indexed for MEDLINE] 16. Am J Med. 1997 Jan 27;102(1A):35S-39S. doi: 10.1016/s0002-9343(97)00415-4. Osteoporosis: prevention, diagnosis, and management. Deal CL(1). Author information: (1)Case Western Reserve University School of Medicine, Cleveland, Ohio, USA. Osteoporosis is a public health scourge that is usually eminently preventable. Some risk factors, such as low calcium...

PubMed Guideline / Consensus Evidence High

European guidance for the diagnosis and management of osteoporosis in postmenopausal women.

Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA | 2019 | Kanis JA, Cooper C, Rizzoli R, Reginster JY

[Indexed for MEDLINE] Conflict of interest statement: JAK reports grants from Amgen, Eli Lilly and Radius Health; non-financial support from Medimaps, and Asahi; and other support from AgNovos. JAK is the architect of FRAX® but has no financial interest. CC reports personal fees from Alliance for Better Bone Health, Amgen, Eli Lilly, GSK, Medtronic, Merck, Novartis, Pfizer, Roc...

PubMed Narrative Review Evidence Moderate

Osteoporosis: A Review.

JAMA | 2025 | Morin SN, Leslie WD, Schousboe JT

[Indexed for MEDLINE] 2. Clin Geriatr Med. 2002 Aug;18(3):529-55. doi: 10.1016/s0749-0690(02)00022-8. Osteoporosis in elderly: prevention and treatment. Srivastava M(1), Deal C. Author information: (1)Section of Geriatric Medicine, A91 Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA. Osteoporosis is a major clinical problem in older women and men. Almo...

PubMed Randomized Controlled Trial Evidence High

Denosumab and teriparatide transitions in postmenopausal osteoporosis (the DATA-Switch study): extension of a randomised controlled trial.

Lancet (London, England) | 2015 | Leder BZ, Tsai JN, Uihlein AV, Wallace PM

[Indexed for MEDLINE] 8. J Endocrinol Invest. 2005;28(10 Suppl):85-9. Raloxifene: bone and cardiovascular effects. Francucci CM(1), Romagni P, Boscaro M. Author information: (1)Division of Endocrinology, Department of Internal Medicine, University of Ancona, Italy. cm.francucci@ao-umbertoprimo.marche.it Raloxifene (RLX), a selective estrogen receptor modulator (SERM), is curren...

PubMed Narrative Review Evidence Moderate

Update on Osteoporosis Screening and Management.

The Medical clinics of North America | 2021 | Anam AK, Insogna K

[Indexed for MEDLINE] Conflict of interest statement: Disclosure The authors have nothing to disclose. 5. Prim Care. 2019 Mar;46(1):175-190. doi: 10.1016/j.pop.2018.10.014. Epub 2018 Dec 24. Update on Osteoporosis. Yedavally-Yellayi S(1), Ho AM(2), Patalinghug EM(2). Author information: (1)Department of Family Medicine, Family Medicine Residency Program, Beaumont Health Troy, 4...

PubMed Narrative Review Evidence Moderate

Risk Factors and Management of Osteoporosis Post-Transplant.

Medicina (Kaunas, Lithuania) | 2020 | Kovvuru K, Kanduri SR, Vaitla P, Marathi R

[Indexed for MEDLINE] Conflict of interest statement: The authors declare no conflict of interest. 15. Nephrol Dial Transplant. 2021 Jan 1;36(1):42-59. doi: 10.1093/ndt/gfaa192. European Consensus Statement on the diagnosis and management of osteoporosis in chronic kidney disease stages G4-G5D. Evenepoel P(1), Cunningham J(2), Ferrari S(3), Haarhaus M(4)(5), Javaid MK(6), Lafag...

PubMed Narrative Review Evidence Moderate

Update on Osteoporosis.

Primary care | 2019 | Yedavally-Yellayi S, Ho AM, Patalinghug EM

[Indexed for MEDLINE] 6. J Steroid Biochem Mol Biol. 2014 Jul;142:155-70. doi: 10.1016/j.jsbmb.2013.09.008. Epub 2013 Oct 29. Prevention and treatment of postmenopausal osteoporosis. Tella SH(1), Gallagher JC(2). Author information: (1)Internal Medicine, Creighton University School of Medicine, 601 N 30th Street, Suite 6718, Omaha, NE 68131, USA. (2)Department of Endocrinology,...

PubMed Narrative Review Evidence Moderate

Should women be screened for osteoporosis at midlife?

Climacteric : the journal of the International Menopause Society | 2018 | de Villiers TJ

[Indexed for MEDLINE] 20. Curr Opin Rheumatol. 2009 Jul;21(4):369-73. doi: 10.1097/BOR.0b013e32832ca41c. Denosumab update. Lewiecki EM(1). Author information: (1)New Mexico Clinical Research & Osteoporosis Center, Albuquerque, New Mexico 87106, USA. LEWIECKI@aol.com PURPOSE OF REVIEW: Denosumab is an investigational fully human monoclonal antibody to receptor activator of nucle...

PubMed Narrative Review Evidence Moderate

Management of severe osteoporosis.

Expert opinion on pharmacotherapy | 2016 | Miller PD

[Indexed for MEDLINE] 14. Medicina (Kaunas). 2020 Jun 19;56(6):302. doi: 10.3390/medicina56060302. Risk Factors and Management of Osteoporosis Post-Transplant. Kovvuru K(1), Kanduri SR(2), Vaitla P(2), Marathi R(3), Gosi S(4), Garcia Anton DF(2), Cabeza Rivera FH(2), Garla V(5). Author information: (1)Department of Medicine, University of Mississippi Medical Center, Jackson, MS...

PubMed Narrative Review Evidence Moderate

Prevention and treatment of postmenopausal osteoporosis.

The Journal of steroid biochemistry and molecular biology | 2014 | Tella SH, Gallagher JC

[Indexed for MEDLINE] 7. Lancet. 2015 Sep 19;386(9999):1147-55. doi: 10.1016/S0140-6736(15)61120-5. Epub 2015 Jul 2. Denosumab and teriparatide transitions in postmenopausal osteoporosis (the DATA-Switch study): extension of a randomised controlled trial. Leder BZ(1), Tsai JN(2), Uihlein AV(2), Wallace PM(2), Lee H(3), Neer RM(2), Burnett-Bowie SA(2). Author information: (1)Dep...

PubMed Narrative Review Evidence Moderate

Obesity and bone.

Current osteoporosis reports | 2013 | Compston J

[Indexed for MEDLINE] 11. JAMA. 2025 Feb 11;333(6):498-508. doi: 10.1001/jama.2024.27154. Screening for Osteoporosis to Prevent Fractures: US Preventive Services Task Force Recommendation Statement. US Preventive Services Task Force; Nicholson WK(1), Silverstein M(2), Wong JB(3), Chelmow D(4), Coker TR(5), Davis EM(6), Jaén CR(7), Krousel-Wood M(8), Lee S(9), Li L(10), Mangione...

PubMed Case Report / Series Evidence Low

Current imaging techniques in osteoporosis.

Clinical and experimental rheumatology | 2018 | Carey JJ, Buehring B

[Indexed for MEDLINE] 19. Climacteric. 2018 Jun;21(3):239-242. doi: 10.1080/13697137.2017.1406914. Epub 2018 Feb 15. Should women be screened for osteoporosis at midlife? de Villiers TJ(1)(2). Author information: (1)a Department of Gynecology, Faculty of Health Sciences , Stellenbosch University , Stellenbosch , South Africa. (2)b Mediclinic Panorama , Cape Town , South Africa....

Crossref Scholarly Work Evidence Unclassified

Drug Therapeutics of Osteoporosis, Vertebral Fracture and Nonunion

Osteoporosis - Pathophysiology, Diagnosis, Management and Therapy | 2023 | Pengguo Gou, Feng Chang

Osteoporosis management is effective in decreasing vertebral fracture risk. The assessment of vertebral fracture risk is used to identify patients with high fracture risk for anti-osteoporotic treatment, especially for those who have not yet fractured. Several pharmacological agents are available to lower vertebral fracture risk by reducing bone resorption or/and stimulating bo...

Crossref Scholarly Work Evidence Unclassified

Immunomodulation of Bone Remodeling in Osteoporosis

Osteoporosis - Pathophysiology, Diagnosis, Management and Therapy | 2023 | Sayantee Hazra, Shagnik Chattopadhyay, Ritobrata Goswami

Reducing bone density and bone quality with increasing propensity of skeletal fracture are the main symptoms of osteoporosis. Disruption of the fine balance between bone formation and resorption leads to this progressive condition, which affects 50% of women and 30% of men after the age of 50. Aging, reduced nutrient (vitamin D and calcium) uptake, suppressed production of estr...

PubMed Narrative Review Evidence Moderate

Glucocorticoid-induced osteoporosis.

Current opinion in endocrinology, diabetes, and obesity | 2007 | Berris KK, Repp AL, Kleerekoper M

[Indexed for MEDLINE] 13. Expert Opin Pharmacother. 2016;17(4):473-88. doi: 10.1517/14656566.2016.1124856. Epub 2015 Dec 23. Management of severe osteoporosis. Miller PD(1). Author information: (1)a University of Colorado Health Sciences Center , Colorado Center for Bone Research , Lakewood , CO , USA. INTRODUCTION: Severe osteoporosis represents a disease of high mortality and...

PubMed Narrative Review Evidence Moderate

Raloxifene: bone and cardiovascular effects.

Journal of endocrinological investigation | 2005 | Francucci CM, Romagni P, Boscaro M

[Indexed for MEDLINE] 9. Osteoporos Int. 2025 Apr;36(4):579-608. doi: 10.1007/s00198-025-07422-3. Epub 2025 Mar 28. Update on the role of bone turnover markers in the diagnosis and management of osteoporosis: a consensus paper from The European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO), International Osteoporo...

PubMed Narrative Review Evidence Moderate

Osteoporosis in elderly: prevention and treatment.

Clinics in geriatric medicine | 2002 | Srivastava M, Deal C

[Indexed for MEDLINE] 3. Osteoporos Int. 2019 Jan;30(1):3-44. doi: 10.1007/s00198-018-4704-5. Epub 2018 Oct 15. European guidance for the diagnosis and management of osteoporosis in postmenopausal women. Kanis JA(1)(2), Cooper C(3)(4), Rizzoli R(5), Reginster JY(6)(7); Scientific Advisory Board of the European Society for Clinical and Economic Aspects of Osteoporosis (ESCEO) an...

PubMed Narrative Review Evidence Moderate

Management of corticosteroid-induced osteoporosis.

Seminars in arthritis and rheumatism | 2000 | Adachi JD, Olszynski WP, Hanley DA, Hodsman AB

[Indexed for MEDLINE] 18. Clin Exp Rheumatol. 2018 Sep-Oct;36 Suppl 114(5):115-126. Epub 2018 Oct 1. Current imaging techniques in osteoporosis. Carey JJ(1), Buehring B(2). Author information: (1)1007, Clinical Sciences Institute, National University of Ireland Galway, and Department of Rheumatic Diseases, Galway University Hospitals, Galway, Ireland. (2)Rheumazentrum Ruhrgebie...

PubMed Narrative Review Evidence Moderate

Osteoporosis: prevention, diagnosis, and management.

The American journal of medicine | 1997 | Deal CL

[Indexed for MEDLINE] 17. Semin Arthritis Rheum. 2000 Feb;29(4):228-51. doi: 10.1016/s0049-0172(00)80011-6. Management of corticosteroid-induced osteoporosis. Adachi JD(1), Olszynski WP, Hanley DA, Hodsman AB, Kendler DL, Siminoski KG, Brown J, Cowden EA, Goltzman D, Ioannidis G, Josse RG, Ste-Marie LG, Tenenhouse AM, Davison KS, Blocka KL, Pollock AP, Sibley J. Author informat...