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Evidence Search

Search reputable indexed orthopaedic literature from multiple scholarly sources, classify the evidence, and link papers directly to wiki topics and cases.

Sources: PubMed, Europe PMC, Crossref

Linking results to Wiki: Biomaterials in Orthopaedics
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Results are classified automatically from source metadata across PubMed, Europe PMC, and Crossref.
PubMed Crossref
PubMed Guideline / Consensus Evidence High

Consensus on Implants in Infections After Spine Surgery.

Clinical spine surgery | 2020 | Divi SN, Kepler CK, Boody BS, Bronson WH

[Indexed for MEDLINE] 14. Biomed Mater. 2020 Nov 21;15(6):062001. doi: 10.1088/1748-605X/aba446. Emerging local delivery strategies to enhance bone regeneration. Elangovan S(1), Gajendrareddy P(2), Ravindran S(3), Salem AK(4). Author information: (1)Department of Periodontics, The University of Iowa College of Dentistry, Iowa City, IA 52242, United States of America. (2)Departm...

PubMed Narrative Review Evidence Moderate

Current developments in orthopaedic implant technology.

Journal of orthopaedic surgery and research | 2025 | Misir A

[Indexed for MEDLINE] Conflict of interest statement: Declarations. Declaration of generative AI and AI-assisted technologies in the writing process: During the preparation of this work the authors used ChatGPT-4, developed by OpenAI (San Francisco, California, USA), to address language related errors. After using this tool/service, the authors reviewed and edited the content a...

PubMed Narrative Review Evidence Moderate

Use of allograft bone matrix in clinical orthopedics.

Regenerative medicine | 2024 | Manawar S, Myrick E, Awad P, Hung V

[Indexed for MEDLINE] Conflict of interest statement: Y Li is one of the executive editors for Journal of Cellular Biochemistry (JCB). All other authors declare no COI or otherwise. The authors have no other competing interests or relevant affiliations with any organization or entity with the subject matter or materials discussed in the manuscript apart from those disclosed. 6....

PubMed Narrative Review Evidence Moderate

The presence of 3D printing in orthopedics: A clinical and material review.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society | 2023 | Rodriguez Colon R, Nayak VV, Parente PEL, Leucht P

[Indexed for MEDLINE] 11. Biomaterials. 2019 Oct;219:119366. doi: 10.1016/j.biomaterials.2019.119366. Epub 2019 Jul 15. Bioinspired surface modification of orthopedic implants for bone tissue engineering. Hu C(1), Ashok D(1), Nisbet DR(1), Gautam V(2). Author information: (1)Research School of Engineering, Australian National University, ACT, 2601, Australia. (2)John Curtin Sch...

PubMed Narrative Review Evidence Moderate

Antimicrobial and Biodegradable 3D Printed Scaffolds for Orthopedic Infections.

ACS biomaterials science & engineering | 2023 | Dubey A, Vahabi H, Kumaravel V

[Indexed for MEDLINE] Conflict of interest statement: The authors declare no competing financial interest. 13. Clin Spine Surg. 2020 May;33(4):163-171. doi: 10.1097/BSD.0000000000000855. Consensus on Implants in Infections After Spine Surgery. Divi SN(1), Kepler CK, Boody BS, Bronson WH, Russo GS, Segar AH, Galetta MS, Goyal DKC, Fang T, Schroeder GD, Vaccaro AR. Author informa...

PubMed Narrative Review Evidence Moderate

Linguistic Analysis Identifies Emergent Biomaterial Fabrication Trends for Orthopaedic Applications.

Advanced healthcare materials | 2023 | Locke RC, Zlotnick HM, Stoeckl BD, Fryhofer GW

[Indexed for MEDLINE] Conflict of interest statement: Declaration of interests The authors declare no conflicts of interest. 19. Nanomedicine (Lond). 2006 Aug;1(2):169-76. doi: 10.2217/17435889.1.2.169. Nanotechnology and biomaterials for orthopedic medical applications. Balasundaram G(1), Webster TJ. Author information: (1)Division of Engineering, Brown University, Providence,...

PubMed Narrative Review Evidence Moderate

Harnessing 4D Printing Bioscaffolds for Advanced Orthopedics.

Small (Weinheim an der Bergstrasse, Germany) | 2022 | Chen X, Han S, Wu W, Wu Z

[Indexed for MEDLINE] 10. J Orthop Res. 2023 Mar;41(3):601-613. doi: 10.1002/jor.25388. Epub 2022 Jun 9. The presence of 3D printing in orthopedics: A clinical and material review. Rodriguez Colon R(1)(2), Nayak VV(3)(4), Parente PEL(5)(6), Leucht P(6)(7), Tovar N(3), Lin CC(6), Rezzadeh K(6), Hacquebord JH(2)(6), Coelho PG(2)(3)(4), Witek L(3)(8). Author information: (1)Icahn...

PubMed Narrative Review Evidence Moderate

Bioengineering Approaches to Fight against Orthopedic Biomaterials Related-Infections.

International journal of molecular sciences | 2022 | Barros J, Monteiro FJ, Ferraz MP

[Indexed for MEDLINE] Conflict of interest statement: The authors declare no conflict of interest. 18. Adv Healthc Mater. 2023 Apr;12(10):e2202591. doi: 10.1002/adhm.202202591. Epub 2023 Feb 5. Linguistic Analysis Identifies Emergent Biomaterial Fabrication Trends for Orthopaedic Applications. Locke RC(1)(2), Zlotnick HM(1)(2)(3), Stoeckl BD(1)(2)(3), Fryhofer GW(1), Galarraga...

PubMed Narrative Review Evidence Moderate

Carbon nanotube-based biomaterials for orthopaedic applications.

Journal of materials chemistry. B | 2020 | Aoki K, Ogihara N, Tanaka M, Haniu H

[Indexed for MEDLINE] 3. J Biomater Sci Polym Ed. 2019 Sep;30(13):1172-1187. doi: 10.1080/09205063.2019.1623989. Epub 2019 Jun 13. 3D bioprinting in orthopedics translational research. Zheng X(1), Huang J(1), Lin J(1), Yang D(2), Xu T(1), Chen D(1), Zan X(2), Wu A(1). Author information: (1)a Department of Orthopaedics , The Second Affiliated Hospital and Yuying Children's Hosp...

PubMed Narrative Review Evidence Moderate

Nanotechnology-based biomaterials for orthopaedic applications: Recent advances and future prospects.

Materials science & engineering. C, Materials for biological applications | 2020 | Kumar S, Nehra M, Kedia D, Dilbaghi N

[Indexed for MEDLINE] 7. J Orthop Surg Res. 2025 Oct 28;20(1):927. doi: 10.1186/s13018-025-06279-w. Current developments in orthopaedic implant technology. Misir A(1)(2). Author information: (1)Department of Orthopedics and Traumatology, Bahçeşehir University Faculty of Medicine, Istanbul, Turkey. misirabdulhamitmd@gmail.com. (2)Medicalpark Goztepe Hospital, Department of Ortho...

PubMed Narrative Review Evidence Moderate

Emerging local delivery strategies to enhance bone regeneration.

Biomedical materials (Bristol, England) | 2020 | Elangovan S, Gajendrareddy P, Ravindran S, Salem AK

[Indexed for MEDLINE] 15. Annu Rev Biomed Eng. 1999;1:19-46. doi: 10.1146/annurev.bioeng.1.1.19. Tissue engineering: orthopedic applications. Laurencin CT(1), Ambrosio AM, Borden MD, Cooper JA Jr. Author information: (1)Center for Advanced Biomaterials and Tissue Engineering, Department of Chemical Engineering, Drexel University, Philadelphia, Pennsylvania 19104, USA. Laurencin...

PubMed Narrative Review Evidence Moderate

Biological Factors, Metals, and Biomaterials Regulating Osteogenesis through Autophagy.

International journal of molecular sciences | 2020 | di Giacomo V, Cataldi A, Sancilio S

[Indexed for MEDLINE] Conflict of interest statement: The authors declare no conflicts of interest. 17. Int J Mol Sci. 2022 Oct 1;23(19):11658. doi: 10.3390/ijms231911658. Bioengineering Approaches to Fight against Orthopedic Biomaterials Related-Infections. Barros J(1)(2)(3), Monteiro FJ(1)(2)(3), Ferraz MP(1)(2)(3). Author information: (1)i3S-Instituto de Investigação e Inova...

PubMed Narrative Review Evidence Moderate

3D bioprinting in orthopedics translational research.

Journal of biomaterials science. Polymer edition | 2019 | Zheng X, Huang J, Lin J, Yang D

[Indexed for MEDLINE] 4. Curr Stem Cell Res Ther. 2016;11(6):452. doi: 10.2174/1574888x1106160617184954. Editorial (Thematic Issues: The Use of Stem Cell Technology in Orthopaedics: Research and Clinical Applications). Cevik Tufan A(1). Author information: (1)Yildirim Beyazit University, School of Medicine, Department of Histology and Embryology, Ankara, Turkey. ceviktufan@yaho...

PubMed Narrative Review Evidence Moderate

Bioinspired surface modification of orthopedic implants for bone tissue engineering.

Biomaterials | 2019 | Hu C, Ashok D, Nisbet DR, Gautam V

[Indexed for MEDLINE] 12. ACS Biomater Sci Eng. 2023 Jul 10;9(7):4020-4044. doi: 10.1021/acsbiomaterials.3c00115. Epub 2023 Jun 20. Antimicrobial and Biodegradable 3D Printed Scaffolds for Orthopedic Infections. Dubey A(1), Vahabi H(2), Kumaravel V(1). Author information: (1)International Centre for Research on Innovative Biobased Materials (ICRI-BioM)─International Research Ag...

PubMed Narrative Review Evidence Moderate

Magnesium-based bioceramics in orthopedic applications.

Acta biomaterialia | 2018 | Nabiyouni M, Brückner T, Zhou H, Gbureck U

[Indexed for MEDLINE] 2. J Mater Chem B. 2020 Oct 21;8(40):9227-9238. doi: 10.1039/d0tb01440k. Carbon nanotube-based biomaterials for orthopaedic applications. Aoki K(1), Ogihara N(2), Tanaka M(3), Haniu H(4), Saito N(5). Author information: (1)Physical Therapy Division, School of Health Sciences, Shinshu University, 3-1-1 Asahi, Matsumoto, Nagano 390-8621, Japan. (2)Department...

Crossref Journal Article Evidence Unclassified

Exploring Ethical Challenges in Orthopedic Practice

Journal of Orthopaedic Case Reports | 2024 | John Mukhopadhaya, Janki Sharan Bhadani, Ashok Shyam

Introduction: The foundation of a successful orthopedic surgeon is built upon medical expertise intertwined with ethical responsibility, where patient care and professional integrity are inseparable. Orthopedic surgeons encounter multifaceted ethical considerations, often navigating gray areas not explicitly addressed in medical education.[1] These challenges demand adherence t...

PubMed Narrative Review Evidence Moderate

Selfprotective smart orthopedic implants.

Expert review of medical devices | 2007 | Parvizi J, Antoci V Jr, Hickok NJ, Shapiro IM

[Indexed for MEDLINE] 9. Small. 2022 Sep;18(36):e2106824. doi: 10.1002/smll.202106824. Epub 2022 Jan 20. Harnessing 4D Printing Bioscaffolds for Advanced Orthopedics. Chen X(1), Han S(2), Wu W(1), Wu Z(1), Yuan Y(1), Wu J(2), Liu C(1). Author information: (1)Key Laboratory for Ultrafine Materials of Ministry of Education, Frontiers Science Center for Materiobiology and Dynamic...

Crossref Journal Article Evidence Unclassified

X-linked Hypophosphatemia. Orthopedic Management in a multidisciplinary setting

Chirurgia Narządów Ruchu i Ortopedia Polska | 2022 | Rudolf Ganger, Aleksandra Stauffer, Christof Radler, Adalbert Raimann

X-linked hypophosphatemia is a rare disorder of bone metabolism caused by inactivating mutations in the PHEX. Conservative therapies such as treatment with phosphate salts or FGF23-inhibiting antibodies can improve symptoms, the latter being superior to the healing of rickets. Recent studies show a high burden of disease of children and adults with XLH. Orthopedic surgeons shou...

PubMed Narrative Review Evidence Moderate

Nanotechnology and biomaterials for orthopedic medical applications.

Nanomedicine (London, England) | 2006 | Balasundaram G, Webster TJ

[Indexed for MEDLINE] 20. Int J Mol Sci. 2026 Feb 25;27(5):2122. doi: 10.3390/ijms27052122. Special Issue: Biomaterials for Dental and Orthopedic Applications. Rimondini L(1), Varoni E(2). Author information: (1)Department of Health Sciences, Università of Piemonte Orientale, 28100 Novara, Italy. (2)Department of Biomedical, Surgical and Dental Sciences, Università degli Studi...

PubMed Original Article Evidence Unclassified

Editorial (Thematic Issues: The Use of Stem Cell Technology in Orthopaedics: Research and Clinical Applications).

Current stem cell research & therapy | 2016 | Cevik Tufan A

[Indexed for MEDLINE] 5. Regen Med. 2024 May 3;19(5):247-256. doi: 10.1080/17460751.2024.2353473. Epub 2024 Jul 19. Use of allograft bone matrix in clinical orthopedics. Manawar S(1), Myrick E(2), Awad P(2), Hung V(2), Hinton C(2), Kenter K(1), Bovid K(1), Li Y(1). Author information: (1)Department of Orthopedic Surgery, Western Michigan University Homer Stryker MD School of Me...

PubMed Narrative Review Evidence Moderate

Tissue engineering: orthopedic applications.

Annual review of biomedical engineering | 1999 | Laurencin CT, Ambrosio AM, Borden MD, Cooper JA Jr

[Indexed for MEDLINE] 16. Int J Mol Sci. 2020 Apr 17;21(8):2789. doi: 10.3390/ijms21082789. Biological Factors, Metals, and Biomaterials Regulating Osteogenesis through Autophagy. di Giacomo V(1), Cataldi A(1), Sancilio S(2). Author information: (1)Department of Pharmacy, University "G. d'Annunzio", 66100 Chieti-Pescara, Italy. (2)Department of Medicine and Ageing Sciences, Uni...